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Paternal Aging Affects Behavior in Pax6 Mutant Mice
- A Gene/Environment Interaction in Understanding Neurodevelopmental Disorders -

Paternal Aging Affects Behavior in Pax6 Mutant Mice
- A Gene/Environment Interaction in Understanding Neurodevelopmental Disorders -

Prof. Osumi and Dr. Yoshizaki of Tohoku University and The Japan Mouse Clinic team indicate that mice with a single genetic risk factor can develop different phenotypes with behavioral abnormalities depending on the paternal age. Our study advocates for serious considerations on the role of paternal aging in breeding strategies for animal studies.
This result is published in the online issue of PLOS ONE on November 18th.